Computational Pathology encompasses linked morphological and molecular tissue characterization. Cancer is a complex multi-faceted disease characterized by heterogeneous coupled tumor and stroma niches and by complex patterns tumor/host immune modulation and response. Accurate multi-scale tissue characterization is crucial to understanding of tumor heterogeneity and immune response. Gaining an understanding of multi-scale systems biology of cancer will play a central role in development, selection and personalization of targeted and immune therapies. Experimental data driving these efforts range from universally acquired Pathology studies scanned in using now inexpensive whole slide imaging platforms to data obtained using high end platforms capable of acquiring combined morphological and highly multiplexed molecular data.
Tissue analysis and modeling is both computation and data intensive – many crucial tasks have resource requirements that extend into and beyond the exascale range. The workshop will bring together researchers to shed light on relationship between cancer signaling pathway alternations, tumor niches, tumor immune suppression and host immune response. The focus of the workshop will be on developing a research agenda to drive computational pathology experimental design, cancer population studies and computational modeling.
Primary Goals for the Meeting:
Meeting History:
The Frontiers of Predictive Oncology and Computing meeting is an annual event tying its origins to the original Biological Applications of Advanced Strategic Computing meetings initiated by Livermore National Laboratory. Bringing a specific focus to the challenges and opportunities for cancer, the first Frontiers of Predictive Oncology and Computing meeting was held July 2016 in Washington DC. At this meeting over 100 thought leaders from industry, government and academia converged to share insights, knowledge and vision for the future of computationally predictive oncology.
This Year's Meeting:
The second Frontiers of Predictive Oncology and Computing meeting brings focus to the topic of “computational pathology”, discussing the broader application of technology, computation and domain expertise to understand and describe the specifics of cancer as a disease. With origins in digital pathology, extended in recent years to include molecular level signatures through sequencing and other forms of enhanced observation, the concept of “computational pathology” embraces the dynamic range of options from virtual microscopy to molecular to probe cancer and capture observations of disease behaviors across space and time scales. The Frontiers of Predictive Oncology and Computing meeting brings context to these methods of observation, providing insight into the key role the collected information plays in the development of computationally predictive oncology models and methods.
Specific Topical areas to be discussed include:
FPOC II is an invitation-only event.
Registration Fees: $250
Registration for this invitation-only event will be opening soon. Please contact Miles Kimbrough (miles.kimbrough@nih.gov) with any questions.
PH: 631-632-4629 | FX: 631-632-4125 | iacs@stonybrook.edu